Question 1

Use the following to answer questions 
Choose the correct answer from the list below. Not all of the answers will be used.
-_______________ is the first amino acid in bacteria and typically is chemically modified.

Accepted Answer

A)  initiation factors
B)  ATP
C)  ricin
D)  one
E)  Shine-DalgarnoF) elongation factor TuG) polysomeH) twoI) kanamycinJ) release factorK) N-formylmethionineL) signal sequenceM) GTPN) H) and K)
O) C) and K)

Question 2

Chloramphenicol acts by:

Accepted Answer

A)   binding to the peptidase cell-wall enzyme.
B)   inhibiting peptidyl transferase activity.
C)   inhibiting protein synthesis.
D)   binding to fMET tRNA.
E)   changing the shape of the mRNA.F) B) and E)
G) A) and E) B

Question 3

Initiation, elongation, and termination all require factors that are members of the __________________ family.

Accepted Answer

The answer of Initiation, elongation, and termination all require factors...

Question 4

What is the mechanism of action of the A fragment of diphtheria toxin?

Accepted Answer

A)   binding the 60S subunit
B)   cleaving tRNA
C)   the chemical modification of EF2
D)   All of the above.
E)   None of the above.F) A) and B)
G) A) and C)

Question 5

What is the role of the translocon in protein synthesis?

Accepted Answer

The translocon is a multi-subu...

Question 6

What is the first step in the elongation cycle?

Accepted Answer

The first step is th...

Question 7

Use the following to answer questions 
Choose the correct answer from the list below. Not all of the answers will be used.
-The biomolecule _______________ delivers the aminoacyl-tRNA to the "A site" in E. coli.

Accepted Answer

A)  initiation factors
B)  ATP
C)  ricin
D)  one
E)  Shine-DalgarnoF) elongation factor TuG) polysomeH) twoI) kanamycinJ) release factorK) N-formylmethionineL) signal sequenceM) GTPN) E) and K)
O) I) and K)

Question 8

What factor(s)  is (are)  necessary for the correct placement of the mRNA and initiating tRNA on the ribosome?

Accepted Answer

A)   IF1
B)   IF2
C)   IF3
D)   A and B
E)   A, B, and CF) B) and E)
G) C) and E)

Question 9

What proteins are involved in the circularization of eukaryotic mRNA?

Accepted Answer

The eIF-4E protein that binds to the mRNA cap is also bound to the poly(A) tail through the eIF-4G protein and the poly(A)-binding protein.

Question 10

What is the direction of translation of mRNA?

Accepted Answer

A)   bidirectional
B)   5` → 3`
C)   3` → 5`
D)   All of the above.
E)   None of the above.F) A) and B)
G) A) and C)

Question 11

In a ribosome, A stands for __________________ and P stands for __________________.

Accepted Answer

The answer of In a ribosome, A stands for __________________...

Question 12

The first amino acid in bacterial proteins is __________________.

Accepted Answer

The answer of The first amino acid in bacterial proteins...

Question 13

Use the following to answer questions 
Choose the correct answer from the list below. Not all of the answers will be used.
-EF-G translocase proteins use the energy of _______________ hydrolysis.

Accepted Answer

A)  initiation factors
B)  ATP
C)  ricin
D)  one
E)  Shine-DalgarnoF) elongation factor TuG) polysomeH) twoI) kanamycinJ) release factorK) N-formylmethionineL) signal sequenceM) GTPN) F) and G)
O) C) and F)

Question 14

What is the order of the tRNA binding sites on the 70S ribosome with respect to the 5′ → 3′ direction of the mRNA?

Accepted Answer

A)   E P A
B)   P A E
C)   A E P
D)   P E A
E)   E A PF) All of the above
G) None of the above

Question 15

What role does the amino acid itself play in the accurate placement of the charged tRNA at the codon?

Accepted Answer

None. Experiments prove that o...

Question 16

In E. coli, the signal sequence that properly aligns the initiation codon in the P site is called the __________________ sequence.

Accepted Answer

The answer of In E. coli, the signal sequence that...

Question 17

Proteins are synthesized in the __________________ direction.

Accepted Answer

N → C, or ...

Question 18

Describe RNAi.

Accepted Answer

RNA interference is a means fo...

Question 19

What is the final destination of proteins directed to the secretory pathway?

Accepted Answer

Proteins sorted into the secretory pathw...

Question 20

Signals that define the beginning and end of protein synthesis are contained in:

Accepted Answer

A)   rRNA.
B)   tRNA.
C)   mRNA.
D)   the ribosome.
E)   protein.F) B) and D)
G) A) and E) C

Exam 40: The Mechanism of Protein Synthesis

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -_______________ is the first amino acid in bacteria and typically is chemically modified.

Correct AnswerverifiedShow Answer

Chloramphenicol acts by:

Correct AnswerverifiedB

Initiation, elongation, and termination all require factors that are members of the __________________ family.

Correct AnswerverifiedShow Answer

What is the mechanism of action of the A fragment of diphtheria toxin?

Correct AnswerverifiedShow Answer

What is the role of the translocon in protein synthesis?

Correct AnswerverifiedThe translocon is a multi-subu...View AnswerShow Answer

What is the first step in the elongation cycle?

Correct AnswerverifiedThe first step is th...View AnswerShow Answer

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -The biomolecule _______________ delivers the aminoacyl-tRNA to the "A site" in E. coli.

Correct AnswerverifiedShow Answer

What factor(s) is (are) necessary for the correct placement of the mRNA and initiating tRNA on the ribosome?

Correct AnswerverifiedShow Answer

What proteins are involved in the circularization of eukaryotic mRNA?

Correct AnswerverifiedThe eIF-4E protein that binds to the mRNA cap is also bound to the poly(A) tail through the eIF-4G protein and the poly(A)-binding protein.

What is the direction of translation of mRNA?

Correct AnswerverifiedShow Answer

In a ribosome, A stands for __________________ and P stands for __________________.

Correct AnswerverifiedShow Answer

The first amino acid in bacterial proteins is __________________.

Correct AnswerverifiedShow Answer

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -EF-G translocase proteins use the energy of _______________ hydrolysis.

Correct AnswerverifiedShow Answer

What is the order of the tRNA binding sites on the 70S ribosome with respect to the 5′ → 3′ direction of the mRNA?

Correct AnswerverifiedShow Answer

What role does the amino acid itself play in the accurate placement of the charged tRNA at the codon?

Correct AnswerverifiedNone. Experiments prove that o...View AnswerShow Answer

In E. coli, the signal sequence that properly aligns the initiation codon in the P site is called the __________________ sequence.

Correct AnswerverifiedShow Answer

Proteins are synthesized in the __________________ direction.

Correct AnswerverifiedN → C, or ...View AnswerShow Answer

Describe RNAi.

Correct AnswerverifiedRNA interference is a means fo...View AnswerShow Answer

What is the final destination of proteins directed to the secretory pathway?

Correct AnswerverifiedProteins sorted into the secretory pathw...View AnswerShow Answer

Signals that define the beginning and end of protein synthesis are contained in:

Correct AnswerverifiedC

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B

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The translocon is a multi-subu...
View Answer

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The first step is th...
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The eIF-4E protein that binds to the mRNA cap is also bound to the poly(A) tail through the eIF-4G protein and the poly(A)-binding protein.

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In a ribosome, A stands for and P stands for .

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None. Experiments prove that o...
View Answer

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N → C, or ...
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RNA interference is a means fo...
View Answer

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Proteins sorted into the secretory pathw...
View Answer

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C